The structure at 100 kings street is surrounded by roads on all four sides and was built by the engineers Whinney, Son and Austen Hall between 1933 and 1935 and features carvings by the local sculptor John Ashton Floyd.
Its neoclassical design is unusual for Manchester, which has led to the parallels with the Big Apple and has inspired the Gotham name.
The ground and basement floors of are currently home to a Jamie’s Italian restaurant and the makeover of the upper seven floors has seen the creation of 60 ‘unique’ hotel rooms.
A key feature of the hotel will be four £300-a-night suites with private ‘indoor gardens’ which are based on a separate, exotic theme.